Nasdaq · Common stock
Ionis Pharmaceuticals (IONS)
$43.42 +$0.49 (+1.14%)
- Day’s range
- $42.76–$43.92
- Volume
- 4.0M
IONS price history
IONS closed at $43.42 on Oct. 26, 2026. Over the past year, its daily close ranged from $42.38 on Oct. 13, 2026 to $86.50 on Feb. 6, 2026.
Data table: IONS daily closes, the past year
| Date | Close |
|---|---|
| Oct. 26, 2026 | $43.42 |
| Oct. 23, 2026 | $42.93 |
| Oct. 22, 2026 | $43.91 |
| Oct. 21, 2026 | $44.27 |
| Oct. 20, 2026 | $45.40 |
| Oct. 19, 2026 | $44.38 |
| Oct. 16, 2026 | $42.94 |
| Oct. 15, 2026 | $44.12 |
| Oct. 14, 2026 | $42.70 |
| Oct. 13, 2026 | $42.38 |
| Oct. 12, 2026 | $43.67 |
| Oct. 9, 2026 | $45.28 |
| Oct. 8, 2026 | $43.30 |
| Oct. 7, 2026 | $44.16 |
| Oct. 6, 2026 | $44.00 |
| Oct. 5, 2026 | $43.50 |
| Oct. 2, 2026 | $43.54 |
| Oct. 1, 2026 | $44.00 |
| Sept. 30, 2026 | $44.65 |
| Sept. 29, 2026 | $45.89 |
| Sept. 28, 2026 | $45.57 |
| Sept. 25, 2026 | $44.50 |
| Sept. 24, 2026 | $43.81 |
| Sept. 23, 2026 | $43.93 |
| Sept. 22, 2026 | $45.75 |
| Sept. 21, 2026 | $44.90 |
| Sept. 18, 2026 | $44.44 |
| Sept. 17, 2026 | $46.75 |
| Sept. 16, 2026 | $44.84 |
| Sept. 15, 2026 | $47.25 |
| Sept. 14, 2026 | $51.44 |
| Sept. 11, 2026 | $54.21 |
| Sept. 10, 2026 | $55.65 |
| Sept. 9, 2026 | $56.02 |
| Sept. 8, 2026 | $56.71 |
| Sept. 4, 2026 | $58.09 |
| Sept. 3, 2026 | $58.13 |
| Sept. 2, 2026 | $61.33 |
| Sept. 1, 2026 | $59.88 |
| Aug. 31, 2026 | $60.36 |
| Aug. 28, 2026 | $61.05 |
| Aug. 27, 2026 | $62.43 |
| Aug. 26, 2026 | $63.36 |
| Aug. 25, 2026 | $63.57 |
| Aug. 24, 2026 | $62.04 |
| Aug. 21, 2026 | $59.74 |
| Aug. 20, 2026 | $58.76 |
| Aug. 19, 2026 | $60.80 |
| Aug. 18, 2026 | $59.62 |
| Aug. 17, 2026 | $58.63 |
| Aug. 14, 2026 | $57.24 |
| Aug. 13, 2026 | $55.87 |
| Aug. 12, 2026 | $56.53 |
| Aug. 11, 2026 | $55.42 |
| Aug. 10, 2026 | $56.94 |
| Aug. 7, 2026 | $56.56 |
| Aug. 6, 2026 | $54.49 |
| Aug. 5, 2026 | $54.19 |
| Aug. 4, 2026 | $55.07 |
| Aug. 3, 2026 | $54.49 |
| July 31, 2026 | $51.77 |
| July 30, 2026 | $53.28 |
| July 29, 2026 | $54.04 |
| July 28, 2026 | $55.30 |
| July 27, 2026 | $55.96 |
| July 24, 2026 | $56.55 |
| July 23, 2026 | $55.87 |
| July 22, 2026 | $54.01 |
| July 21, 2026 | $53.39 |
| July 20, 2026 | $52.95 |
| July 17, 2026 | $54.39 |
| July 16, 2026 | $54.65 |
| July 15, 2026 | $54.73 |
| July 14, 2026 | $54.93 |
| July 13, 2026 | $56.75 |
| July 10, 2026 | $58.25 |
| July 9, 2026 | $64.27 |
| July 8, 2026 | $84.46 |
| July 7, 2026 | $86.33 |
| July 6, 2026 | $83.18 |
| July 2, 2026 | $81.80 |
| July 1, 2026 | $79.19 |
| June 30, 2026 | $79.29 |
| June 29, 2026 | $80.69 |
| June 26, 2026 | $81.18 |
| June 25, 2026 | $78.34 |
| June 24, 2026 | $76.52 |
| June 23, 2026 | $75.99 |
| June 22, 2026 | $75.89 |
| June 18, 2026 | $74.12 |
| June 17, 2026 | $74.31 |
| June 16, 2026 | $73.09 |
| June 15, 2026 | $73.96 |
| June 12, 2026 | $73.28 |
| June 11, 2026 | $73.82 |
| June 10, 2026 | $73.32 |
| June 9, 2026 | $74.58 |
| June 8, 2026 | $73.54 |
| June 5, 2026 | $74.48 |
| June 4, 2026 | $75.13 |
| June 3, 2026 | $73.82 |
| June 2, 2026 | $72.97 |
| June 1, 2026 | $75.38 |
| May 29, 2026 | $76.50 |
| May 28, 2026 | $77.33 |
| May 27, 2026 | $76.49 |
| May 26, 2026 | $76.07 |
| May 22, 2026 | $75.56 |
| May 21, 2026 | $75.78 |
| May 20, 2026 | $75.06 |
| May 19, 2026 | $73.84 |
| May 18, 2026 | $72.52 |
| May 15, 2026 | $74.23 |
| May 14, 2026 | $75.68 |
| May 13, 2026 | $77.60 |
| May 12, 2026 | $75.83 |
| May 11, 2026 | $75.38 |
| May 8, 2026 | $75.71 |
| May 7, 2026 | $76.02 |
| May 6, 2026 | $76.85 |
| May 5, 2026 | $75.25 |
| May 4, 2026 | $75.45 |
| May 1, 2026 | $75.28 |
| April 30, 2026 | $74.76 |
| April 29, 2026 | $74.83 |
| April 28, 2026 | $71.78 |
| April 27, 2026 | $72.23 |
| April 24, 2026 | $73.27 |
| April 23, 2026 | $74.09 |
| April 22, 2026 | $74.83 |
| April 21, 2026 | $74.78 |
| April 20, 2026 | $74.87 |
| April 17, 2026 | $75.71 |
| April 16, 2026 | $75.26 |
| April 15, 2026 | $76.82 |
| April 14, 2026 | $76.76 |
| April 13, 2026 | $74.95 |
| April 10, 2026 | $75.17 |
| April 9, 2026 | $76.43 |
| April 8, 2026 | $74.98 |
| April 7, 2026 | $73.89 |
| April 6, 2026 | $74.33 |
| April 2, 2026 | $74.79 |
| April 1, 2026 | $75.13 |
| March 31, 2026 | $75.09 |
| March 30, 2026 | $72.52 |
| March 27, 2026 | $72.15 |
| March 26, 2026 | $74.24 |
| March 25, 2026 | $72.70 |
| March 24, 2026 | $69.68 |
| March 23, 2026 | $70.79 |
| March 20, 2026 | $70.99 |
| March 19, 2026 | $71.32 |
| March 18, 2026 | $71.67 |
| March 17, 2026 | $72.33 |
| March 16, 2026 | $72.34 |
| March 13, 2026 | $71.19 |
| March 12, 2026 | $72.34 |
| March 11, 2026 | $74.79 |
| March 10, 2026 | $75.66 |
| March 9, 2026 | $75.36 |
| March 6, 2026 | $74.04 |
| March 5, 2026 | $75.16 |
| March 4, 2026 | $79.45 |
| March 3, 2026 | $78.66 |
| March 2, 2026 | $81.96 |
| Feb. 27, 2026 | $81.15 |
| Feb. 26, 2026 | $80.60 |
| Feb. 25, 2026 | $80.93 |
| Feb. 24, 2026 | $85.45 |
| Feb. 23, 2026 | $84.60 |
| Feb. 20, 2026 | $83.15 |
| Feb. 19, 2026 | $83.15 |
| Feb. 18, 2026 | $82.22 |
| Feb. 17, 2026 | $81.36 |
| Feb. 13, 2026 | $80.60 |
| Feb. 12, 2026 | $81.78 |
| Feb. 11, 2026 | $84.35 |
| Feb. 10, 2026 | $84.29 |
| Feb. 9, 2026 | $84.79 |
| Feb. 6, 2026 | $86.50 |
| Feb. 5, 2026 | $83.48 |
| Feb. 4, 2026 | $84.99 |
| Feb. 3, 2026 | $84.59 |
| Feb. 2, 2026 | $83.07 |
| Jan. 30, 2026 | $82.67 |
| Jan. 29, 2026 | $83.88 |
| Jan. 28, 2026 | $81.92 |
| Jan. 27, 2026 | $82.14 |
| Jan. 26, 2026 | $81.00 |
| Jan. 23, 2026 | $80.29 |
| Jan. 22, 2026 | $81.79 |
| Jan. 21, 2026 | $79.44 |
| Jan. 20, 2026 | $77.53 |
| Jan. 16, 2026 | $76.33 |
| Jan. 15, 2026 | $77.21 |
| Jan. 14, 2026 | $78.87 |
| Jan. 13, 2026 | $79.48 |
| Jan. 12, 2026 | $81.66 |
| Jan. 9, 2026 | $80.30 |
| Jan. 8, 2026 | $81.54 |
| Jan. 7, 2026 | $83.17 |
| Jan. 6, 2026 | $81.49 |
| Jan. 5, 2026 | $78.53 |
| Jan. 2, 2026 | $79.67 |
| Dec. 31, 2025 | $79.11 |
| Dec. 30, 2025 | $78.97 |
| Dec. 29, 2025 | $79.98 |
| Dec. 26, 2025 | $79.93 |
| Dec. 24, 2025 | $80.65 |
| Dec. 23, 2025 | $80.33 |
| Dec. 22, 2025 | $81.34 |
| Dec. 19, 2025 | $79.57 |
| Dec. 18, 2025 | $77.63 |
| Dec. 17, 2025 | $77.08 |
| Dec. 16, 2025 | $78.37 |
| Dec. 15, 2025 | $79.76 |
| Dec. 12, 2025 | $80.82 |
| Dec. 11, 2025 | $79.14 |
| Dec. 10, 2025 | $78.63 |
| Dec. 9, 2025 | $78.86 |
| Dec. 8, 2025 | $81.51 |
| Dec. 5, 2025 | $81.68 |
| Dec. 4, 2025 | $81.81 |
| Dec. 3, 2025 | $81.84 |
| Dec. 2, 2025 | $81.31 |
| Dec. 1, 2025 | $81.99 |
| Nov. 28, 2025 | $82.73 |
| Nov. 26, 2025 | $82.70 |
| Nov. 25, 2025 | $80.93 |
| Nov. 24, 2025 | $78.52 |
| Nov. 21, 2025 | $76.09 |
| Nov. 20, 2025 | $73.12 |
| Nov. 19, 2025 | $74.00 |
| Nov. 18, 2025 | $74.50 |
| Nov. 17, 2025 | $73.26 |
| Nov. 14, 2025 | $71.55 |
| Nov. 13, 2025 | $69.84 |
| Nov. 12, 2025 | $72.67 |
| Nov. 11, 2025 | $72.45 |
| Nov. 10, 2025 | $69.54 |
| Nov. 7, 2025 | $73.55 |
| Nov. 6, 2025 | $74.10 |
| Nov. 5, 2025 | $74.68 |
| Nov. 4, 2025 | $72.88 |
| Nov. 3, 2025 | $73.65 |
| Oct. 31, 2025 | $74.30 |
| Oct. 30, 2025 | $74.17 |
| Oct. 29, 2025 | $71.88 |
| Oct. 28, 2025 | $73.57 |
| Oct. 27, 2025 | $72.99 |
Key figures
- 52-week range
- $42.38–$86.50Low Oct. 13, 2026; high Feb. 6, 2026
- Average daily volume
- 3.2MPast 3 months
- Market value
- $7.22B
- Dividend yield
- —
- From 52-week high
- −49.80%
Price change
- 1 month
- −2.43%
- 3 months
- −23.22%
- Year to date
- −45.11%
- 1 year
- −38.72%
$1,000 a year ago
$1,000 put into IONS at the close on Oct. 24, 2025 would be worth $613.
Price only, dividends not included.
What Wall Street says about IONS
In the past 90 days, Wall Street firms published 19 rating or price-target actions on IONS: 2 upgrades, 1 new rating, 4 reiterated ratings, 2 raised price targets and 10 lowered price targets.
| Action | Rating | |||
|---|---|---|---|---|
| BMO Capital | Upgrade | Market perform to Outperform | $54 to $66 | |
| UBS | Upgrade | Neutral to Buy | $46 to $88 | |
| HC Wainwright & Co. | Reiterates | Buy | $100 | |
| JP Morgan | Cuts target | Overweight | $76 to $70 | |
| Guggenheim | Cuts target | Buy | $89 to $80 | |
| Barclays | Cuts target | Overweight | $90 to $85 | |
| BMO Capital | Cuts target | Market perform | $61 to $54 | |
| Canaccord Genuity | Cuts target | Buy | $95 to $85 | |
| Goldman Sachs | Cuts target | Neutral | $69 to $56 | |
| HC Wainwright & Co. | Cuts target | Buy | $115 to $100 | |
| Morgan Stanley | Cuts target | Overweight | $110 to $104 | |
| BMO Capital | Raises target | Market perform | $60 to $61 | |
| HC Wainwright & Co. | Reiterates | Buy | $115 | |
| Needham | Reiterates | Buy | $86 | |
| HC Wainwright & Co. | Reiterates | Buy | $115 | |
| BMO Capital | Initiates coverage | Outperform to Market perform | $60 | |
| JP Morgan | Raises target | Overweight | $72 to $76 | |
| HC Wainwright & Co. | Cuts target | Buy | $125 to $115 | |
| Wells Fargo | Cuts target | Overweight | $100 to $95 |
Ratings and price targets are the firms’ own opinions, reported as published.
Not investment advice.
About Ionis Pharmaceuticals, Inc. Common Stock
Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).
- Headquarters
- Carlsbad, Calif.
- Employees
- 1,402
- Listed
- May 17, 1991
- Sector
- Health care
- Industry
- Pharmaceutical preparations
In WallStreetDigest editions
No WallStreetDigest article about IONS is on the site yet.