Nasdaq · Common stock
Septerna (SEPN)
$41.38 +$0.97 (+2.40%)
- Day’s range
- $38.39–$41.95
- Volume
- 279,433
SEPN price history
SEPN closed at $41.38 on Oct. 26, 2026. Over the past year, its daily close ranged from $18.10 on Nov. 10, 2025 to $48.19 on Aug. 12, 2026.
Data table: SEPN daily closes, the past year
| Date | Close |
|---|---|
| Oct. 26, 2026 | $41.38 |
| Oct. 23, 2026 | $40.41 |
| Oct. 22, 2026 | $40.88 |
| Oct. 21, 2026 | $40.76 |
| Oct. 20, 2026 | $39.35 |
| Oct. 19, 2026 | $36.38 |
| Oct. 16, 2026 | $36.35 |
| Oct. 15, 2026 | $37.45 |
| Oct. 14, 2026 | $36.32 |
| Oct. 13, 2026 | $36.42 |
| Oct. 12, 2026 | $37.56 |
| Oct. 9, 2026 | $38.37 |
| Oct. 8, 2026 | $36.90 |
| Oct. 7, 2026 | $36.00 |
| Oct. 6, 2026 | $35.67 |
| Oct. 5, 2026 | $37.87 |
| Oct. 2, 2026 | $37.71 |
| Oct. 1, 2026 | $38.05 |
| Sept. 30, 2026 | $39.13 |
| Sept. 29, 2026 | $39.13 |
| Sept. 28, 2026 | $39.74 |
| Sept. 25, 2026 | $37.77 |
| Sept. 24, 2026 | $38.13 |
| Sept. 23, 2026 | $38.45 |
| Sept. 22, 2026 | $40.38 |
| Sept. 21, 2026 | $38.54 |
| Sept. 18, 2026 | $38.69 |
| Sept. 17, 2026 | $39.50 |
| Sept. 16, 2026 | $38.44 |
| Sept. 15, 2026 | $38.86 |
| Sept. 14, 2026 | $39.55 |
| Sept. 11, 2026 | $38.51 |
| Sept. 10, 2026 | $37.75 |
| Sept. 9, 2026 | $37.97 |
| Sept. 8, 2026 | $37.37 |
| Sept. 4, 2026 | $36.75 |
| Sept. 3, 2026 | $36.80 |
| Sept. 2, 2026 | $37.50 |
| Sept. 1, 2026 | $37.68 |
| Aug. 31, 2026 | $38.15 |
| Aug. 28, 2026 | $38.91 |
| Aug. 27, 2026 | $40.47 |
| Aug. 26, 2026 | $40.25 |
| Aug. 25, 2026 | $41.30 |
| Aug. 24, 2026 | $40.52 |
| Aug. 21, 2026 | $40.00 |
| Aug. 20, 2026 | $40.79 |
| Aug. 19, 2026 | $43.93 |
| Aug. 18, 2026 | $43.80 |
| Aug. 17, 2026 | $44.20 |
| Aug. 14, 2026 | $44.50 |
| Aug. 13, 2026 | $45.14 |
| Aug. 12, 2026 | $48.19 |
| Aug. 11, 2026 | $47.76 |
| Aug. 10, 2026 | $38.85 |
| Aug. 7, 2026 | $38.83 |
| Aug. 6, 2026 | $39.53 |
| Aug. 5, 2026 | $38.76 |
| Aug. 4, 2026 | $38.98 |
| Aug. 3, 2026 | $34.98 |
| July 31, 2026 | $34.45 |
| July 30, 2026 | $35.18 |
| July 29, 2026 | $33.61 |
| July 28, 2026 | $33.97 |
| July 27, 2026 | $33.49 |
| July 24, 2026 | $33.10 |
| July 23, 2026 | $33.47 |
| July 22, 2026 | $34.20 |
| July 21, 2026 | $33.68 |
| July 20, 2026 | $32.21 |
| July 17, 2026 | $33.40 |
| July 16, 2026 | $31.56 |
| July 15, 2026 | $34.07 |
| July 14, 2026 | $34.54 |
| July 13, 2026 | $34.36 |
| July 10, 2026 | $35.93 |
| July 9, 2026 | $37.84 |
| July 8, 2026 | $36.40 |
| July 7, 2026 | $35.83 |
| July 6, 2026 | $33.47 |
| July 2, 2026 | $34.00 |
| July 1, 2026 | $34.61 |
| June 30, 2026 | $33.49 |
| June 29, 2026 | $34.75 |
| June 26, 2026 | $37.34 |
| June 25, 2026 | $34.54 |
| June 24, 2026 | $36.05 |
| June 23, 2026 | $36.57 |
| June 22, 2026 | $34.85 |
| June 18, 2026 | $36.17 |
| June 17, 2026 | $35.80 |
| June 16, 2026 | $35.17 |
| June 15, 2026 | $36.03 |
| June 12, 2026 | $35.95 |
| June 11, 2026 | $34.03 |
| June 10, 2026 | $30.47 |
| June 9, 2026 | $31.01 |
| June 8, 2026 | $30.41 |
| June 5, 2026 | $31.15 |
| June 4, 2026 | $31.37 |
| June 3, 2026 | $30.55 |
| June 2, 2026 | $29.94 |
| June 1, 2026 | $29.98 |
| May 29, 2026 | $30.20 |
| May 28, 2026 | $31.05 |
| May 27, 2026 | $29.79 |
| May 26, 2026 | $30.65 |
| May 22, 2026 | $28.36 |
| May 21, 2026 | $27.92 |
| May 20, 2026 | $28.01 |
| May 19, 2026 | $26.51 |
| May 18, 2026 | $26.30 |
| May 15, 2026 | $26.95 |
| May 14, 2026 | $28.32 |
| May 13, 2026 | $24.75 |
| May 12, 2026 | $24.84 |
| May 11, 2026 | $23.57 |
| May 8, 2026 | $23.87 |
| May 7, 2026 | $23.98 |
| May 6, 2026 | $24.71 |
| May 5, 2026 | $24.13 |
| May 4, 2026 | $24.82 |
| May 1, 2026 | $23.61 |
| April 30, 2026 | $23.76 |
| April 29, 2026 | $23.45 |
| April 28, 2026 | $24.29 |
| April 27, 2026 | $25.09 |
| April 24, 2026 | $24.67 |
| April 23, 2026 | $24.97 |
| April 22, 2026 | $25.86 |
| April 21, 2026 | $25.80 |
| April 20, 2026 | $26.86 |
| April 17, 2026 | $26.13 |
| April 16, 2026 | $24.99 |
| April 15, 2026 | $25.93 |
| April 14, 2026 | $24.13 |
| April 13, 2026 | $23.34 |
| April 10, 2026 | $23.09 |
| April 9, 2026 | $24.83 |
| April 8, 2026 | $24.49 |
| April 7, 2026 | $24.84 |
| April 6, 2026 | $24.78 |
| April 2, 2026 | $25.18 |
| April 1, 2026 | $24.37 |
| March 31, 2026 | $24.03 |
| March 30, 2026 | $23.30 |
| March 27, 2026 | $23.87 |
| March 26, 2026 | $24.74 |
| March 25, 2026 | $24.21 |
| March 24, 2026 | $23.44 |
| March 23, 2026 | $23.78 |
| March 20, 2026 | $24.18 |
| March 19, 2026 | $24.28 |
| March 18, 2026 | $24.11 |
| March 17, 2026 | $25.17 |
| March 16, 2026 | $25.14 |
| March 13, 2026 | $25.14 |
| March 12, 2026 | $26.45 |
| March 11, 2026 | $26.31 |
| March 10, 2026 | $28.02 |
| March 9, 2026 | $29.06 |
| March 6, 2026 | $28.78 |
| March 5, 2026 | $27.47 |
| March 4, 2026 | $28.83 |
| March 3, 2026 | $28.13 |
| March 2, 2026 | $28.64 |
| Feb. 27, 2026 | $29.02 |
| Feb. 26, 2026 | $30.28 |
| Feb. 25, 2026 | $29.99 |
| Feb. 24, 2026 | $30.86 |
| Feb. 23, 2026 | $28.00 |
| Feb. 20, 2026 | $27.28 |
| Feb. 19, 2026 | $27.08 |
| Feb. 18, 2026 | $28.30 |
| Feb. 17, 2026 | $30.30 |
| Feb. 13, 2026 | $27.50 |
| Feb. 12, 2026 | $25.76 |
| Feb. 11, 2026 | $26.34 |
| Feb. 10, 2026 | $26.70 |
| Feb. 9, 2026 | $26.59 |
| Feb. 6, 2026 | $25.41 |
| Feb. 5, 2026 | $24.44 |
| Feb. 4, 2026 | $24.93 |
| Feb. 3, 2026 | $25.54 |
| Feb. 2, 2026 | $25.03 |
| Jan. 30, 2026 | $23.34 |
| Jan. 29, 2026 | $23.80 |
| Jan. 28, 2026 | $23.66 |
| Jan. 27, 2026 | $25.45 |
| Jan. 26, 2026 | $25.97 |
| Jan. 23, 2026 | $25.77 |
| Jan. 22, 2026 | $26.67 |
| Jan. 21, 2026 | $26.35 |
| Jan. 20, 2026 | $27.03 |
| Jan. 16, 2026 | $26.07 |
| Jan. 15, 2026 | $27.38 |
| Jan. 14, 2026 | $26.73 |
| Jan. 13, 2026 | $26.38 |
| Jan. 12, 2026 | $24.88 |
| Jan. 9, 2026 | $25.30 |
| Jan. 8, 2026 | $25.74 |
| Jan. 7, 2026 | $26.41 |
| Jan. 6, 2026 | $25.45 |
| Jan. 5, 2026 | $26.79 |
| Jan. 2, 2026 | $27.98 |
| Dec. 31, 2025 | $27.88 |
| Dec. 30, 2025 | $27.78 |
| Dec. 29, 2025 | $28.38 |
| Dec. 26, 2025 | $28.62 |
| Dec. 24, 2025 | $29.47 |
| Dec. 23, 2025 | $28.23 |
| Dec. 22, 2025 | $29.47 |
| Dec. 19, 2025 | $29.58 |
| Dec. 18, 2025 | $27.54 |
| Dec. 17, 2025 | $26.55 |
| Dec. 16, 2025 | $26.23 |
| Dec. 15, 2025 | $27.18 |
| Dec. 12, 2025 | $25.44 |
| Dec. 11, 2025 | $26.21 |
| Dec. 10, 2025 | $25.64 |
| Dec. 9, 2025 | $25.49 |
| Dec. 8, 2025 | $25.96 |
| Dec. 5, 2025 | $26.76 |
| Dec. 4, 2025 | $26.16 |
| Dec. 3, 2025 | $26.55 |
| Dec. 2, 2025 | $26.17 |
| Dec. 1, 2025 | $27.62 |
| Nov. 28, 2025 | $29.02 |
| Nov. 26, 2025 | $29.57 |
| Nov. 25, 2025 | $27.97 |
| Nov. 24, 2025 | $28.51 |
| Nov. 21, 2025 | $25.56 |
| Nov. 20, 2025 | $23.77 |
| Nov. 19, 2025 | $23.10 |
| Nov. 18, 2025 | $21.69 |
| Nov. 17, 2025 | $21.64 |
| Nov. 14, 2025 | $23.27 |
| Nov. 13, 2025 | $19.24 |
| Nov. 12, 2025 | $19.23 |
| Nov. 11, 2025 | $19.24 |
| Nov. 10, 2025 | $18.10 |
| Nov. 7, 2025 | $18.51 |
| Nov. 6, 2025 | $18.80 |
| Nov. 5, 2025 | $19.13 |
| Nov. 4, 2025 | $19.46 |
| Nov. 3, 2025 | $20.05 |
| Oct. 31, 2025 | $20.60 |
| Oct. 30, 2025 | $21.49 |
| Oct. 29, 2025 | $21.94 |
| Oct. 28, 2025 | $22.32 |
| Oct. 27, 2025 | $22.62 |
Key figures
- 52-week range
- $18.10–$48.19Low Nov. 10, 2025; high Aug. 12, 2026
- Average daily volume
- 390,805Past 3 months
- Market value
- $1.93B
- Dividend yield
- —
- From 52-week high
- −14.13%
Price change
- 1 month
- +9.56%
- 3 months
- +25.02%
- Year to date
- +48.42%
- 1 year
- +90.96%
$1,000 a year ago
$1,000 put into SEPN at the close on Oct. 24, 2025 would be worth $1,910.
Price only, dividends not included.
What Wall Street says about SEPN
In the past 90 days, Wall Street firms published 5 rating or price-target actions on SEPN: 5 raised price targets.
| Action | Rating | |||
|---|---|---|---|---|
| JP Morgan | Raises target | Overweight | $38 to $48 | |
| Jones Trading | Raises target | Buy | $43 to $62 | |
| HC Wainwright & Co. | Raises target | Buy | $40 to $60 | |
| Wells Fargo | Raises target | Overweight | $48 to $50 | |
| Guggenheim | Raises target | Buy | $45 to $51 |
Ratings and price targets are the firms’ own opinions, reported as published.
Not investment advice.
About Septerna, Inc. Common Stock
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
- Headquarters
- South San Francisco, Calif.
- Employees
- 130
- Listed
- Oct. 25, 2024
- Sector
- Health care
- Industry
- Pharmaceutical preparations
In WallStreetDigest editions
No WallStreetDigest article about SEPN is on the site yet.